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Observe Carefully (2)pentobarbital will minimize the level or outcome of suvorexant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of. Solid CYP3A4 inducers might decrease suvorexant efficacy; if greater suvorexant dose needed, never exceed 20 mg/daypentobarbital will lessen the level or impact of lonafarnib by inf